Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats

Medial prefrontal cortex (mPFC), amygdala, and striatum neurocircuitry has been shown to play an important role in post-traumatic stress disorder (PTSD) pathology in humans. Clinical studies show hypoactivity in the mPFC and hyperactivity in the amygdala and striatum of PTSD patients, which has been...

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Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	Veronica M. Piggott, Kelly E. Bosse, Michael J. Lisieski, John A. Strader, Jeffrey A. Stanley, Alana C. Conti, Farhad Ghoddoussi, Shane A. Perrine
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-04-01
Subjects:	post-traumatic stress disorder single-prolonged stress 1H-MRS MEMRI striatum amygdala
Online Access:	https://www.frontiersin.org/article/10.3389/fnbeh.2019.00018/full