Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD).

Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic perturbation...

Full description

Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Jung H Suh, Bindu Kanathezhath, Swapna Shenvi, Hua Guo, Alicia Zhou, Anureet Tiwana, Frans Kuypers, Bruce N Ames, Mark C Walters
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24558439/pdf/?tool=EBI