Sequencing accuracy and systematic errors of nanopore direct RNA sequencing

Abstract Background Direct RNA sequencing (dRNA-seq) on the Oxford Nanopore Technologies (ONT) platforms can produce reads covering up to full-length gene transcripts, while containing decipherable information about RNA base modifications and poly-A tail lengths. Although many published studies have...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Wang Liu-Wei, Wiep van der Toorn, Patrick Bohn, Martin Hölzer, Redmond P. Smyth, Max von Kleist
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Nanopore sequencing Direct RNA sequencing Transcriptomics Epitranscriptomics Sequencing errors Sequencing accuracy
Online Access:	https://doi.org/10.1186/s12864-024-10440-w