CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome

Viruses completely depend on the host translational machinery, but their genomes are often enriched in rare codons and therefore should be translated with poor efficiency. Here, Jungfleisch et al. apply Ribo-Seq and RNASeq to provide a global view on the translational changes occurring during Chikun...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Jennifer Jungfleisch, René Böttcher, Marc Talló-Parra, Gemma Pérez-Vilaró, Andres Merits, Eva Maria Novoa, Juana Díez
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Online Access:	https://doi.org/10.1038/s41467-022-31835-x