Cerebrospinal fluid biomarkers provide evidence for kidney-brain axis involvement in cerebral malaria pathogenesis

IntroductionCerebral malaria is one of the most severe manifestations of malaria and is a leading cause of acquired neurodisability in African children. Recent studies suggest acute kidney injury (AKI) is a risk factor for brain injury in cerebral malaria. The present study evaluates potential mecha...

Full description

Bibliographic Details

Published in:	Frontiers in Human Neuroscience
Main Authors:	Andrea L. Conroy, Dibyadyuti Datta, Robert O. Opoka, Anthony Batte, Paul Bangirana, Adnan Gopinadhan, Kagan A. Mellencamp, Ayse Akcan-Arikan, Richard Idro, Chandy C. John
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	cerebral malaria blood-brain-barrier cerebrospinal fluid acute kidney injury uremia brain injury
Online Access:	https://www.frontiersin.org/articles/10.3389/fnhum.2023.1177242/full