High fat diet and PCSK9 knockout modulates lipid profile of the liver and changes the expression of lipid homeostasis related genes

Abstract Background High fat diet (HFD) increases the likelihood of dyslipidemia, which can be a serious risk factor for atherosclerosis, diabetes or hepatosteatosis. Although changes in different blood lipid levels were broadly investigated, such alterations in the liver tissue have not been studie...

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Bibliographic Details

Published in:	Nutrition & Metabolism
Main Authors:	Krisztina Németh, Blanka Tóth, Farkas Sarnyai, Anna Koncz, Dorina Lenzinger, Éva Kereszturi, Tamás Visnovitz, Brachyahu Meir Kestecher, Xabier Osteikoetxea, Miklós Csala, Edit I. Buzás, Viola Tamási
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Subjects:	Liver Dyslipidemia Hepatosteatosis PCSK9 LDLR CD36
Online Access:	https://doi.org/10.1186/s12986-023-00738-z