A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging

Fluorescent imaging in the second biological window has advantages for in vivo applications. Here, the authors synthesise a molecular nanoprobe which activates upon binding H2O2, generating both strong fluorescent NIR-II emission and ultrasound signal for multi-mode imaging of inflammatory diseases.

Bibliographic Details
Published in:Nature Communications
Main Authors: Junjie Chen, Longqi Chen, Yinglong Wu, Yichang Fang, Fang Zeng, Shuizhu Wu, Yanli Zhao
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Online Access:https://doi.org/10.1038/s41467-021-27233-4