Roles of Post-translational Modifications in Spinocerebellar Ataxias

Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions. Therefore, PTMs are vital regulatory mechanisms for...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Linlin Wan, Keqin Xu, Zhao Chen, Beisha Tang, Hong Jiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-09-01
Subjects:	post-translational modification spinocerebellar ataxias protein pathogenesis therapy
Online Access:	https://www.frontiersin.org/article/10.3389/fncel.2018.00290/full