Minimally invasive detection of early-stage opisthorchiasis-associated cholangiocarcinoma using label-free surface-enhanced Raman spectroscopy (SERS) of hamster serum.

<h4>Background</h4>Cholangiocarcinoma (CCA) is a deadly cancer often detected late. Current diagnostic methods, such as ultrasound and invasive biopsies, have limitations; there is a critical need for a rapid, minimally invasive and effective strategy for the early diagnosis and staging...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Apisit Chaidee, Suppakrit Kongsintaweesuk, Thatsanapong Pongking, Keerapach Tunbenjasiri, Aye Myat Mon, Chawalit Pairojkul, Pakornkiat Tanasuka, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang, Naruechar Charoenram, David Blair, Somchai Pinlaor
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0334916