Impaired Spatial Learning and Memory in Middle-Aged Mice with Kindling-Induced Spontaneous Recurrent Seizures

Temporal lobe epilepsy is the most common and often drug-resistant type of epilepsy in the adult and aging populations and has great diversity in etiology, electro-clinical manifestations, and comorbidities. Kindling through repeated brief stimulation of limbic structures is a commonly used model of...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Haiyu Liu, Kurt R. Stover, Nila Sivanenthiran, Jonathan Chow, Chloe Cheng, Yapeng Liu, Stellar Lim, Chiping Wu, Donald F. Weaver, James H. Eubanks, Hongmei Song, Liang Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-09-01
Subjects:	epilepsy hippocampus kindling mice memory
Online Access:	https://www.frontiersin.org/article/10.3389/fphar.2019.01077/full