Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study

Abstract Sex differences in drug pharmacokinetics include variations in the expression of the cytochrome P450 enzymes, which are involved in the metabolism of benzodiazepines. It is unclear whether sex influences outcomes associated with intranasally administered drugs. A post hoc analysis of sex di...

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Bibliographic Details

Published in:	Epilepsia Open
Main Authors:	James W. Wheless, Robert Edward Hogan, Charles S. Davis, Enrique Carrazana, Adrian L. Rabinowicz
Format:	Article
Language:	English
Published:	Wiley 2024-04-01
Subjects:	acute repetitive seizures benzodiazepines diazepam gender intranasal sex
Online Access:	https://doi.org/10.1002/epi4.12907