HOXD10 regulates intestinal permeability and inhibits inflammation of dextran sulfate sodium-induced ulcerative colitis through the inactivation of the Rho/ROCK/MMPs axis

Ulcerative colitis (UC) has been identified as a severe inflammatory disease with significantly increased incidence across the world. The detailed role and mechanism of HOXD10 in UC remain unclear. In present study, we found that HOXD10 was lowly expressed in UC samples and was notably decreased by...

Full description

Bibliographic Details

Published in:	Open Medicine
Main Authors:	Xu Jing, Lin Nana
Format:	Article
Language:	English
Published:	De Gruyter 2024-05-01
Subjects:	ulcerative colitis hoxd10 inflammatory response intestinal barrier function rho/rock/mmps axis
Online Access:	https://doi.org/10.1515/med-2023-0844