Synthesis, crystal structure, Hirshfeld surface analysis, and DFT calculation of 4-(5-(((1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazol-4-yl)methyl)thio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine

Triazole is considered as a privileged scaffold in medicinal chemistry by virtue of it is diverse biological activity. several drugs currently in the market possess triazole moiety. In this study click chemistry was performed on the pyridine based 1,2,4-triazole-tethered propargyl moiety to afford 4...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Mohamed El-Naggar, Kamrul Hasan, Monther A. Khanfar, Fatima-Azzahra Delmani, Ihsan A. Shehadi, Raed Al-Qawasmeh, Hussein M. Elmehdi
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Subjects:	1,2,3-Triazole Pyridine X-ray structure Hirshfeld analysis And DFT
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024163499