Prenatal Sildenafil and Fetal-placental Programming in Human Pregnancies Complicated by Fetal Growth Restriction: A Retrospective Gene Expression Analysis

Objective: Fetal growth restricted (FGR) offspring are more susceptible to develop cardiovascular and renal disease. The potential therapeutic value of sildenafil to improve fetal growth has recently been evaluated in several randomized clinical trials. Here we investigate whether administration of...

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Bibliographic Details

Published in:	Journal of Trial and Error
Main Authors:	Fieke Terstappen, Torsten Plösch, Jorg J.A. Calis, Wessel Ganzevoort, Anouk Pels, Nina D. Paauw, Sanne J. Gordijn, Bas B. van Rijn, Michal Mokry, A. Titia Lely
Format:	Article
Language:	English
Published:	JOTE Publishers 2023-09-01
Subjects:	fetal growth restriction sildenafil developmental programming RNA-sequencing gene set enrichment analysis human umbilical cord vein endothelial cells placenta
Online Access:	https://journal.trialanderror.org/pub/prenatal-sildenafil-pregnancies