Histone H4K16 acetylation modification regulated autophagy and apoptosis in neuron after spinal cord injury

Abstract Autophagy maintains the homeostasis of the internal environment by clearing misfolded proteins and damaged organelles, which can reduce neuronal apoptosis in the early stage of spinal cord injury (SCI) and promote neural function recovery. Previous studies have shown that decreased acetylat...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Jie-Min Lin, Kun-Hui Li, Lin-Quan Zhou, De-Hui Chen, Xin Zhao, Wen-Wen Li, Wen-Ge Liu
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Subjects:	Spinal cord injury H4K16ac Autophagy Apoptosis
Online Access:	https://doi.org/10.1038/s41598-025-10352-z