A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids

Abstract Extracellular vesicles (EVs) carry complex glycoproteins critical mediators of disease progression and hold great potential for liquid biopsy applications. However, their low abundance presents significant analytical challenges. This study develop a versatile platform for EV N-glycoproteomi...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Mingyang Li, Xiaorong Song, Haixia Tu, Jie Sun, Yuanyuan Deng, Bing Wang, Yuhan Cai, Yulian Wang, Bin Li, Yue Wang, Xiangzheng Zhang, Dong Wei, Xiaoyu Yang, Yueshuai Guo, Xiang Li, Jie Gu, Jie Ni, Yifan Zhou, Zhongze Gu, Zhuoying Xie, Yan Li, Xuejiang Guo
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Online Access:	https://doi.org/10.1038/s41467-025-63075-0