Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer

Tumor-specific targeting with fluorescent probes can enhance contrast for identification of cancer during surgical resection and visualize otherwise invisible tumor margins. Nanobodies are the smallest naturally-occurring antigen-binding molecules with rapid pharmacokinetics. The present work demons...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Thinzar M. Lwin, Michael A. Turner, Hiroto Nishino, Siamak Amirfakhri, Sophie Hernot, Robert M. Hoffman, Michael Bouvet
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	nanobodies pancreatic cancer patient derived orthotopic xenograft CEA fluorescence-guided-surgery fluorescence
Online Access:	https://www.mdpi.com/2218-273X/12/5/711