Dicer regulates differentiation and viability during mouse pancreatic cancer initiation.

miRNA levels are altered in pancreatic ductal adenocarcinoma (PDA), the most common and lethal pancreatic malignancy, and intact miRNA processing is essential for lineage specification during pancreatic development. However, the role of miRNA processing in PDA has not been explored. Here we study th...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: John P Morris, Renee Greer, Holger A Russ, Guido von Figura, Grace E Kim, Anke Busch, Jonghyeob Lee, Klemens J Hertel, Seung Kim, Michael McManus, Matthias Hebrok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095486&type=printable