LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy

Abstract Various low-density lipoprotein receptors (LPRs) have been identified as entry factors for alphaviruses, and structures of the corresponding virion-receptor complexes have been determined. Here, we analyze the similarities and differences in the receptor binding modes of multiple alphavirus...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Ningning Wang, Andres Merits, Michael Veit, Laura Sandra Lello, Shuhan Kong, Houqi Jiao, Jie Chen, Yu Wang, Georgi Dobrikov, Félix A. Rey, Shuo Su
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Online Access:https://doi.org/10.1038/s41467-024-49301-1