Biological and therapeutic implications of RKIP in Gastrointestinal Stromal Tumor (GIST): an integrated transcriptomic and proteomic analysis

Abstract Background Gastrointestinal stromal tumors (GIST) represent a significant clinical challenge due to their metastatic potential and limited treatment options. Raf kinase inhibitor protein (RKIP), a suppressor of the MAPK signaling pathway, is downregulated in various cancers and acts as a me...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cancer Cell International
المؤلفون الرئيسيون: Nathália Cristina Campanella, Izabela Natalia Faria Gomes, Ana Laura Vieira Alves, Leticia Ferro Leal, Adriane Feijó Evangelista, Marcela Nunes Rosa, Matias Eliseo Melendez, Viviane Aline Oliveira Silva, Richard Lucas Konichi Dias, Lucas Faria Abrahão-Machado, Iara Santana, Olga Martinho, Denise Peixoto Guimarães, Vitor Marcel Faça, Rui Manuel Reis
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2023-10-01
الموضوعات:
RKIP expression
Gene knockout
GIST
COL3A1
Collagen
Cell invasion
الوصول للمادة أونلاين:https://doi.org/10.1186/s12935-023-03102-6

الانترنت

https://doi.org/10.1186/s12935-023-03102-6

مواد مشابهة