The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches

Abstract Glioblastoma (GBM) is a highly aggressive brain tumor associated with limited therapeutic options and a poor prognosis. CXCR3, a chemokine receptor, serves dual autocrine–paracrine functions in cancer. Despite gaps in our understanding of the functional role of the CXCR3 receptor in GBM, it...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Travis Yui Hei Chan, Jenny Sum Yee Wong, Karrie Mei-Yee Kiang, Cherry Won Yuet Sun, Gilberto Ka-Kit Leung
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-12-01
Online Access:	https://doi.org/10.1038/s41419-023-06354-2