The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches

Abstract Glioblastoma (GBM) is a highly aggressive brain tumor associated with limited therapeutic options and a poor prognosis. CXCR3, a chemokine receptor, serves dual autocrine–paracrine functions in cancer. Despite gaps in our understanding of the functional role of the CXCR3 receptor in GBM, it...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Death and Disease
المؤلفون الرئيسيون: Travis Yui Hei Chan, Jenny Sum Yee Wong, Karrie Mei-Yee Kiang, Cherry Won Yuet Sun, Gilberto Ka-Kit Leung
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Publishing Group 2023-12-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41419-023-06354-2