At short telomeres Tel1 directs early replication and phosphorylates Rif1.
The replication time of Saccharomyces cerevisiae telomeres responds to TG1-3 repeat length, with telomeres of normal length replicating late during S phase and short telomeres replicating early. Here we show that Tel1 kinase, which is recruited to short telomeres, specifies their early replication,...
| 發表在: | PLoS Genetics |
|---|---|
| Main Authors: | , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Public Library of Science (PLoS)
2014-10-01
|
| 在線閱讀: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004691&type=printable |