Effect of exogenous trivalent iron ions on tau phosphorylation and aggregation in SH-SY5Y cells

BackgroundA large amount of iron deposition in the brain can cause neuronal damage by inducing oxidative stress, neuroinflammation, and abnormal mitochondrial function. In addition, iron deposition is also reported to be closely related to the pathogenesis of Alzheimer's disease (AD). The neuro...

Full description

Bibliographic Details
Published in:环境与职业医学
Main Authors: Zhina ZHANG, Zhuoran WANG, Mingxuan YANG, Yanli ZHANG, Guowei LIU, Shu FANG, Qiang SU, Qiao NIU, Junhong GUO
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2023-03-01
Subjects:
sh-sy5y cell
exogenous trivalent iron ion
neurofibrillary tangle
tau hyperphosphorylation
tau aggregation
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM22272

Internet

http://www.jeom.org/article/cn/10.11836/JEOM22272

Similar Items