Computational Modeling of Tumor Response to Drug Release from Vasculature-Bound Nanoparticles.

Systemically injected nanoparticle (NPs) targeting tumor vasculature offer a venue for anti-angiogenic therapies as well as cancer detection and imaging. Clinical application has been limited, however, due to the challenge of elucidating the complex interplay of nanotechnology, drug, and tumor param...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Louis T Curtis, Min Wu, John Lowengrub, Paolo Decuzzi, Hermann B Frieboes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144888&type=printable