NAPE-PLD regulates specific baseline affective behaviors but is dispensable for inflammatory hyperalgesia

N-acyl-ethanolamine (NAEs) serve as key endogenous lipid mediators as revealed by manipulation of fatty acid amide hydrolase (FAAH), the primary enzyme responsible for metabolizing NAEs. Preclinical studies focused on FAAH or NAE receptors indicate an important role for NAE signaling in nociception...

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Bibliographic Details

Published in:	Neurobiology of Pain
Main Authors:	Irene Chen, Laura B. Murdaugh, Cristina Miliano, Yuyang Dong, Ann M. Gregus, Matthew W. Buczynski
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	Endocannabinoids Lipids Sex difference Depression Hyperalgesia Arthritis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452073X23000223