Methylome-wide and meQTL analysis helps to distinguish treatment response from non-response and pathogenesis markers in schizophrenia

Schizophrenia is a complex condition with entwined genetic and epigenetic risk factors, posing a challenge to disentangle the intermixed pathological and therapeutic epigenetic signatures. To resolve this, we performed 850K methylome-wide and 700K genome-wide studies on the same set of schizophrenia...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Binithamol K. Polakkattil, Neetha N. Vellichirammal, Indu V. Nair, Chandrasekharan M. Nair, Moinak Banerjee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	schizophrenia epigenetics methylation SNP genotyping gene expression treatment response
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1297760/full