An optimized deep learning approach for blood-brain barrier permeability prediction with ODE integration

Blood-brain barrier (BBB) permeability prediction plays a pivotal role in drug discovery for neurological disorders which is essential for the development of central nervous system (CNS) drugs. Compounds having high permeability must be found to synthesize brain drugs for the treatment of different...

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Bibliographic Details

Published in:	Informatics in Medicine Unlocked
Main Authors:	Nimra Aftab, Fahad Masood, Sajjad Ahmad, Saqib Shahid Rahim, Samira Sanami, Bilal Shaker, Dong-Qing Wei
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	Blood-brain barrier Convolutional neural networks Long short-term memory Ordinary differential equation Alzheimer's disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352914824000820