β-Elemene alleviates cisplatin resistance in oral squamous cell carcinoma cell via inhibiting JAK2/STAT3 pathway in vitro and in vivo
Abstract Objective To investigate the effect of β-Elemene (β-Ele) on the cisplatin sensitivity of OSCC cells and its mechanism in vitro and in vivo. Methods The human OSCC cell lines Tca-8113 and the cisplatin-resistant cell line Tca-8113-CDDP were cultured with β-Ele or/and cisplatin. The cytotoxic...
| Published in: | Cancer Cell International |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-07-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12935-022-02650-7 |