Spatialsmooth: a spatially-aware convolutional autoencoder framework for enhanced deconvolution of spatial transcriptomics data

Abstract Spatial transcriptomics technologies have revolutionized our understanding of tissue heterogeneity by providing gene expression data with spatial context. However, due to the limited resolution of some of these techniques, multiple cell types are often captured at each spatial location. Sev...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMC Genomics
المؤلفون الرئيسيون: Xiao Yang, Jinjin Xiang, Yanbin Feng, Yanfang Zhao, Huamei Li, Xiaozhou Chen
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2025-09-01
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1186/s12864-025-11959-2