SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation

Abstract Platinum-based chemotherapy remains one of the major choices for treatment of ovarian cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency, thereby causing chemotherapy failure and poor prognosis. SH3 domain containing ring finger 2 (SH3RF2) has been l...

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Bibliographic Details
Published in:Communications Biology
Main Authors: Ting-Ting Gong, Fang-Hua Liu, Qian Xiao, Yi-Zi Li, Yi-Fan Wei, He-Li Xu, Fan Cao, Ming-Li Sun, Feng-Li Jiang, Tao Tao, Qi-Peng Ma, Xue Qin, Yang Song, Song Gao, Lang Wu, Yu-Hong Zhao, Dong-Hui Huang, Qi-Jun Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Online Access:https://doi.org/10.1038/s42003-023-05721-1