Altered IL-7 signaling in CD4+ T cells from patients with visceral leishmaniasis.

<h4>Background</h4>CD4+ T cells play a central role in control of L. donovani infection, through IFN-γ production required for activation of macrophages and killing of intracellular parasites. Impaired control of parasites can in part be explained by hampered CD4+ T cells effector functi...

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Bibliographic Details
Published in:PLoS Neglected Tropical Diseases
Main Authors: Shashi Kumar, Shashi Bhushan Chauhan, Shreya Upadhyay, Siddharth Sankar Singh, Vimal Verma, Rajiv Kumar, Christian Engwerda, Susanne Nylén, Shyam Sundar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011960&type=printable