A sucrose-rich diet promotes Clostridioides difficile carriage without prior antibiotics and significantly exacerbates both acute disease and long-term colonization

Clostridioides difficile is a major cause of healthcare-associated diarrhea, with rising rates of community-acquired infections and asymptomatic carriage. While antibiotic exposure is a well-established risk factor, the role of diet in modulating susceptibility remains underexplored. Here, we demons...

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Bibliographic Details

Published in:	Gut Microbes
Main Authors:	Daniel Erickson, Michelle Chua, Katelyn R. Sheneman, Lily Hernandez, James Collins
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Clostridioides difficile asymptomatic carriage colonization resistance gut microbiome high-sugar diet
Online Access:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2566302