Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice

N-methyl-N-nitrosourea (MNU) is widely used to study the mechanism of retinal degenerative diseases (RDs) because of its selectivity of photoreceptor cell death. Many reports suggest that excessive nitric oxide (NO) plays a crucial role in neuronal cell death. We hypothesized that nitric oxide synth...

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Bibliographic Details

Published in:	Journal of Pharmacological Sciences
Main Authors:	Yoshiki Koriyama, Suguru Hisano, Kazuhiro Ogai, Kayo Sugitani, Ayako Furukawa, Satoru Kato
Format:	Article
Language:	English
Published:	Elsevier 2015-03-01
Subjects:	Neurotoxicity Nitric oxide Retina
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861315000407