T Regulatory Cells and Priming the Suppressive Tumor Microenvironment

Treg play a central role in maintenance of self tolerance and homeostasis through suppression of self-reactive T cell populations. In addition to that role, Treg also survey cancers and suppress anti-tumor immune responses. Thus, understanding the unique attributes of Treg-tumor interactions may per...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Christina M. Paluskievicz, Xuefang Cao, Reza Abdi, Pan Zheng, Yang Liu, Jonathan S. Bromberg
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-10-01
Subjects:	Treg immunosuppression tumor microenvironment metastasis anti-tumor immunity
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02453/full