Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep‐phenotyping case report

Abstract Introduction Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a participant with DS who was nondemented at baseline but developed dementia after 5 years. Methods Throughout the course...

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Bibliographic Details

Published in:	Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Main Authors:	Elijah Mak, Anastasia Bickerton, Concepcion Padilla, Madeleine J. Walpert, Tiina Annus, Liam R. Wilson, Young T. Hong, Tim D. Fryer, Jonathan P. Coles, Franklin I. Aigbirhio, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, David K. Menon, Peter J. Nestor, Shahid H. Zaman, Anthony J. Holland
Format:	Article
Language:	English
Published:	Wiley 2019-12-01
Online Access:	https://doi.org/10.1016/j.dadm.2019.04.006