Methylation patterns at the adjacent CpG sites within enhancers are a part of cell identity

Abstract Background It is generally accepted that methylation status of CpG sites spaced up to 50 bp apart is correlated, and accumulation of locally disordered methylation at adjacent CpG sites is involved in neoplastic transformation, acting in similar way as stochastic accumulation of mutations....

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Bibliographic Details
Published in:Epigenetics & Chromatin
Main Authors: Olga Taryma-Leśniak, Jan Bińkowski, Patrycja Kamila Przybylowicz, Katarzyna Ewa Sokolowska, Konrad Borowski, Tomasz Kazimierz Wojdacz
Format: Article
Language:English
Published: BMC 2024-10-01
Subjects:
Epigenomics
Epigenetics
DNA methylation
Co-methylation
Methylation patterns
Online Access:https://doi.org/10.1186/s13072-024-00555-5

Internet

https://doi.org/10.1186/s13072-024-00555-5

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