Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability

Cryptotanshinone (CTS) is a plant product extracted from Salvia miltiorrhiza Bunge with various pharmacological significances. In addition to its activities against coronary heart disease, hyperlipidemia, stroke, hepatitis and chronic renal failure, it demonstrates antimetastatic effects. However, i...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Wenzheng Zhao, Bohao Ruan, Xiaoyi Sun, Zhenwei Yu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Subjects:	cryptotanshinone nanocrystals pharmacokinetics poloxamer 407 oral administration
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1122071/full