Photocatalytic Enantioselective Radical Cascade Multicomponent Minisci Reaction of β‐Carbolines Using Diazo Compounds as Radical Precursors

Abstract Here, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and enantioselectivity (up to 83% yield and 95% ee)....

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Bibliographic Details
Published in:Advanced Science
Main Authors: Yi‐Jie Gu, Mu‐Peng Luo, Hua Yuan, Guo‐Kai Liu, Shou‐Guo Wang
Format: Article
Language:English
Published: Wiley 2024-07-01
Subjects:
Online Access:https://doi.org/10.1002/advs.202402272