Triflamidation of Allyl-Containing Substances:Unusual Dehydrobromination vs. Intramolecular Heterocyclization

Allyl halides with triflamide under oxidative conditions form halogen-substituted amidines. Allyl cyanide reacts with triflamide in acetonitrile or THF solutions in the presence of NBS to give the products of bromotriflamidation with a solvent interception, whereas in CH₂Cl<...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Anton S. Ganin, Mikhail Yu. Moskalik, Ivan A. Garagan, Vera V. Astakhova, Bagrat A. Shainyan
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	allyl cyanide allyl halides triflamide oxidative bromotriflamidation solvent interception heterocyclization
Online Access:	https://www.mdpi.com/1420-3049/27/20/6910