Gene-dose effects of APOE ε4 on age-dependent increases in Peak Width of Skeletonised Mean Diffusivity during midlife

Introduction: The mechanistic associations between small vessel disease (SVD) and dementia are still poorly understood. The APOE ε4 allele, recognised as the strongest genetic risk factor for Alzheimer's disease, has been previously implicated in SVD, although it remains unclear whether this as...

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發表在:	Cerebral Circulation - Cognition and Behavior
Main Authors:	Elijah Mak, Maria-Eleni Dounavi, Audrey Low, Graciela Muniz Terrera, Paresh Malhotra, Ivan Koychev, Clare Mackay, Brian Lawlor, Lorina Naci, Katie Wells, Craig Ritchie, Karen Ritchie, Li Su, Juan Gispert, John O'Brien
格式:	Article
語言:	英语
出版:	Elsevier 2024-01-01
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2666245024000941