Dietary disodium fumarate supplementation alleviates subacute ruminal acidosis (SARA)-induced liver damage by inhibiting pyroptosis via mitophagy-NLRP3 inflammasome pathway in lactating Hu sheep

Liver damage is common in ruminants with subacute ruminal acidosis (SARA). Disodium fumarate (DF) could regulate rumen microbial community and neutralize ruminal organic acids. This study aimed to evaluate the effect of dietary DF supplementation on SARA-induced liver damage and investigate the unde...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Immunology
المؤلفون الرئيسيون:	Hongzhu Zhang, Huimin Shi, Shendong Zhou, Guozhen Wei, Wan Xie, Meijuan Meng, Guangjun Chang, Xiangzhen Shen
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2023-05-01
الموضوعات:	SARA liver damage NLRP3 inflammasome pyroptosis mitophagy
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197133/full