GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy

Abstract Abnormal proliferation of mesangial cells is a hallmark of diabetic nephropathy (DN). However, the cellular signaling mechanisms that regulate this proliferation remain poorly understood. In this study, it is demonstrated that GA‐binding protein (GABP), a member of the ETS family of transcr...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Lei Du, Sijie Liu, Yinfei Lu, Dongxue Ren, Xiujuan Yu, Yue Hu, Tingting Yang, Qun Yang, Jingxian Ming, Jiawei Zhang, Xiaoxing Yin, Qian Lu
Format:	Article
Language:	English
Published:	Wiley 2025-04-01
Subjects:	diabetic nephropathy GABP GLI1 mesangial cell proliferation renal fibrosis
Online Access:	https://doi.org/10.1002/advs.202407462