TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration

Abstract Background The reactivation of genetic programs from early development is a common mechanism for injury-induced organ regeneration. T-box 3 (TBX3) is a member of the T-box family of transcription factors previously shown to regulate pluripotency and subsequent lineage commitment in a number...

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Bibliographic Details

Published in:	BMC Biology
Main Authors:	Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M. Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M. Moon, Lukas Perkhofer, Alexander Kleger
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Subjects:	Pancreatic development TBX3 Acute pancreatitis Organ regeneration Embryonic development
Online Access:	https://doi.org/10.1186/s12915-023-01553-x