Targeting miR-337 mitigates disuse-induced bone loss

Abstract Disuse-induced bone loss occurs in long-term bed-ridden patients and in astronauts during spaceflight. The underlying mechanisms are poorly understood. In a rodent model of disuse-induced bone loss (called hindlimb unloading (HU)), we observed that decreased numbers of leptin receptor (LepR...

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Bibliographic Details
Published in:Cell Discovery
Main Authors: Jiao Li, Ding Ma, Chunxue Zhang, Xueling Zheng, Ruihan Hao, Bin Zuo, Fei Xiao, Yang Li, Yuhang Liu, Zhouyi Duan, Yao Xiong, Orion R. Fan, Wenmin Zhu, Liming Dai, Bingjun Zhang, Yi Eve Sun, Xiaoling Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Online Access:https://doi.org/10.1038/s41421-025-00822-z

Internet

https://doi.org/10.1038/s41421-025-00822-z

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