Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-ENEMA FMT Trial)

IntroductionIrritable bowel syndrome (IBS) is a functional bowel disorder. Gut dysbiosis involves in pathogenesis of IBS. Limited studies compared efficacy of fecal microbiota transplantation (FMT) via different routes of administration. This study aimed to compare efficacy of encapsulated FMT, FMT...

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Published in:	Frontiers in Medicine
Main Authors:	Natsuda Aumpan, Soonthorn Chonprasertsuk, Bubpha Pornthisarn, Sith Siramolpiwat, Patommatat Bhanthumkomol, Navapan Issariyakulkarn, Pornpen Gamnarai, Phubordee Bongkotvirawan, Arti Wongcha-um, Varocha Mahachai, Ratha-korn Vilaichone
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	fecal microbiota transplantation irritable bowel syndrome capsule rectal enema fecal transplant
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1648944/full