GOLPH3: a Golgi phosphatidylinositol(4)phosphate effector that directs vesicle trafficking and drives cancer

GOLPH3 is a peripheral membrane protein localized to the Golgi and its vesicles, but its purpose had been unclear. We found that GOLPH3 binds specifically to the phosphoinositide phosphatidylinositol(4)phosphate [PtdIns(4)P], which functions at the Golgi to promote vesicle exit for trafficking to th...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Ramya S. Kuna, Seth J. Field
Format:	Article
Language:	English
Published:	Elsevier 2019-02-01
Subjects:	lipids phosphoinositides phospholipids/trafficking cell signaling Golgi apparatus myosin 18A
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520326389