Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

Human fetal midbrain tissue grafting has provided proof-of-concept for dopamine cell replacement therapy (CRT) in Parkinson's disease (PD). However, limited tissue availability has hindered the development and widespread use of this experimental therapy. Here we present a method for generating...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Diogo Ribeiro, Rocio Laguna Goya, Geeta Ravindran, Romina Vuono, Clare L. Parish, Claire Foldi, Tobias Piroth, Shanzheng Yang, Malin Parmar, Guido Nikkhah, Jens Hjerling-Leffler, Olle Lindvall, Roger A. Barker, Ernest Arenas
Format:	Article
Language:	English
Published:	Elsevier 2013-01-01
Subjects:	Dopaminergic Human fetal ventral midbrain
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996112002938