Multi-omics reveals deoxycholic acid modulates bile acid metabolism via the gut microbiota to antagonize carbon tetrachloride-induced chronic liver injury

ABSTRACTDeoxycholic acid (DCA) serves essential functions in both physiological and pathological liver processes; nevertheless, the relationship among DCA, gut microbiota, and metabolism in chronic liver injury remain insufficiently understood. The primary objective of this study is to elucidate the...

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Bibliographic Details

Published in:	Gut Microbes
Main Authors:	Li Zhang, Zhiyi Zheng, Huanhuan Huang, Ya Fu, Tianbin Chen, Can Liu, Qiang Yi, Caorui Lin, Yongjun Zeng, Qishui Ou, Yongbin Zeng
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Chronic liver injury gut microbiota metabolism transcriptome inflammation deoxycholic acid
Online Access:	https://www.tandfonline.com/doi/10.1080/19490976.2024.2323236