Expression of dengue virus and Zika virus NS2B-NS3pro constructs alter cellular fatty acids, but co-expression with a Zika virus virus-like particle is detrimental to virus-like particle expression

Abstract Objective Studies have shown that Flavivirus infection remodels the host cell to favour viral replication. In particular, the host cell lipid profile is altered, and it has been proposed that this process alters membrane fluidity to allow wrapping of the outer structural proteins around the...

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Bibliographic Details

Published in:	BMC Research Notes
Main Authors:	Suwipa Ramphan, Nathamon Yimpring, Chontida Tangsongcharoen, Suthatta Sornprasert, Atitaya Hitakarun, Wannapa Sornjai, Sittiruk Roytrakul, Atikorn Panya, Duncan R. Smith
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	Dengue virus Zika virus NS3 protease Lipid Fatty acid methyl esters Virus-like particles
Online Access:	https://doi.org/10.1186/s13104-023-06572-z